The 'Madden NFL' video games have sold 85 million copies and generated more than $3 billion in revenue

"You can measure the impact of "Madden" through its sales: as many as 2 million copies in a single week, 85 million copies since the game's inception and more than $3 billion in total revenue. You can chart the game's ascent, shoulder to shoulder, alongside the $20 billion-a-year video game industry, which is either co-opting Hollywood (see "Tomb Raider" and "Prince of Persia") or topping it (opening-week gross of "Call of Duty: Modern Warfare 2": $550 million; "The Dark Knight": $204 million)."
Source:  ESPN, August 2010